Elastosis perforans serpiginosa (EPS) is a rare disorder classified as a primary perforating dermatosis. That group of diseases also includes. Four types of elastosis perforans serpiginosa (EPS) have been described in literature: 1) idiopathic EPS, 2) reactive perforating elastosis. Elastosis perforans serpiginosa (EPS) is a rare dermatologic condition where connective and elastic tissues are viewed as foreign objects and subsequently.
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However, the irritation subsided after a few weeks of therapy. In our case, we chose treatment with topical 0. This is described as transepithelial elimination and results in a group of small reddish bumps.
A biopsy was serpigknosa approximately 1 year before her presentation to our institution. Over time, the skin lesions had spread peripherally with some central clearing.
Elastosis perforans serpiginosa is considered as mild dermatosis, which is not accompanied by involvement of other organs [ 2 ]. Views Read Edit View history. The lesions were fusing into an annular arrangement, spreading outwards and leaving erythematous macule in the center Figures 1 A, B.
On physical examination, she was noted to have erythematous annular and arcuate keratotic plaques on the anterior aspect of her neck and right arm Figure 2. A year-old woman was referred to our institution for evaluation of a prutitic “nonhealing scar” that had been present on the posterolateral aspect of the left side of her neck for 1 year.
Elastosis elastosia serpiginosa is a disorder in which altered elastic fibers are recognized as foreign material and are extruded through the epidermis by transepidermal elimination. Tazarotene may have comedolytic properties that allow for the unplugging of transepidermal pores in this disease. It appears to be more common in males than females ratio 4: D ICD – Though numerous treatment modalities have been described in the literature, most are not very effective.
This article has been cited by. Open in a separate window. While the exact pathogenic process of EPS remains unknown, associations with various underlying systemic conditions and connective tissue disorders have been reported in the literature, including Down’s syndrome, osteogenesis perfoeans, scleroderma, acrogeria, Ehlers-Danlos syndrome type IV vascular typeMarfan syndrome, Rothmund-Thomson syndrome, cutis laxa, diabetes mellitus, perforating folliculitis, and chronic renal failure 89.
If you have any concerns with your skin or its treatment, see a dermatologist for advice. Penicillamine-induced elastosis of the mucosal lip.
Infobox medical condition new All stub articles. Corresponding author and reprints: Copyright American Medical Association.
Elastosis perforans serpiginosa
perforana In the latter case, the treatment has not been undertaken [ 6 ]. Published online Feb None, Conflict of Interest: The mechanism of action of tazarotene in treating EPS is unknown.
Histopathologic picture of EPS with thick epidermis and transepidermal channel A—Chorny plug A, C and mixed inflammatory infiltration within the dermis B. In the first case, initially they unsuccessfully used 3-month therapy with tretinoin cream, then cryotherapy was performed, yielding only a minimal improvement.
Adjacent inflammation with dermal necrosis, both within and surrounding the epithelia, was evident. In cases of EPS associated with penicillamine therapy, the characteristic skin lesions typically develop within the first year of treatment and can be histologically distinguished from the other forms of EPS by the presence of calcium deposits in perfoarns elastic fibers 7.
Oxford University Press; Table 1 summarizes the clinical data from four cases of EPS in the Korean literature in addition to our case. Tazarotene is the first receptor-selective topical retinoid approved for the treatment of plaque psoriasis. EPS presents as a cluster of small reddish bumps mm in diameter, often grouped in linearcircular or serpiginous snake-like patterns.
After obtaining the result of the histopathological examination, the nature of the disease, possibilities as well as the effectiveness and purpose of the treatment were explained to the parents.
Elastosis Perforans Serpiginosa
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Abnormalities of dermal fibrous and elastic tissue Cutaneous condition stubs. Table 1 Diseases associated with elastosis perforans serpiginosa.
This page was last edited on 2 Mayat A summary of the 5 cases of elastosis perforance serpiginosa reported in the Korean literature including our case.
How to cite this URL: Physical examination revealed multiple 2- to 7-mm crusted, erythematous, ulcerated papules and plaques with an arcuate configuration.
The patient was treated unsuccessfully with cryotherapy approximately 6 times; high-potency topical corticosteroids, including clobetasol and halobetasol, for 6 weeks; topical 0. Author information Article notes Copyright and License information Disclaimer. YAG laser and pulsed dye lasers.